Clinical Trial: Mesalazine for Irritable Bowel Syndrome with Diarrhea (IBS-D), United Kingdom

January 27, 2013

The Nottingham University Hospitals Trust, King’s Mill Hospital Mansfield, Derby Royal Hospital and Wythenshawe Hospital Manchester are looking for men and women age 18-75 with Rome III criteria diarrhea-predominant IBS to participate in a clinical trial of the medication mesalazine for the treatment of IBS. Other eligibility requirements or exclusions may apply.  Mesalazine is a common, established treatment for inflammatory bowel disease (IBD). Because of recent research showing that chronic, low-level gut inflammation may be a factor in irritable bowel syndrome, the researchers hypothesize that mesalazine may be an effective treatment for IBS as well.

The study involves 4 hospital visits of 1-2 hours each over the course of 14 weeks. Participants will receive either a placebo or mesalazine in a double-blind protocol, meaning neither the volunteers nor the doctor or nurse will be aware of whether specific individuals are given mesalazine or a placebo.

Volunteers who complete the study will be paid 150 pounds as compensation for expenses or time off from employment.

For further information, contact Dr Ching Lam (Clinical Research Fellow) at or 01159249924 ext 7061.

IBS Impact has summarized this information from a posting on the website of the IBS Network, the national charity for irritable bowel syndrome in the U.K. and this study’s current listing at, a worldwide database that is administered by the United States National Institutes of Health.

Being Voices and Faces for Irritable Bowel Syndrome (IBS)

January 20, 2013

Some relatively recent followers of IBS Impact may not be aware that our main website includes an entire section devoted to IBS awareness or support for family members and friends of those with IBS. The section includes several articles, as well as the link to a University of North Carolina  Center for Functional GI and Motility Disorders past “Evening with the Experts” video on partner burden and IBS. This mix of resources includes perspectives from people with IBS, a family member and professionals in three countries so far, and are directed at general audiences, spouses or partners or parents of children with IBS. We are very pleased by the current submissions and once again, publicly thank past contributors for agreeing to our requests, volunteering their own stories or granting permission to link. However, true awareness is most effective with a large number of varied experiences. As such, new readers and followers are now invited to submit their own articles for consideration.

The content of these personal stories and articles is fairly open-ended, whether you are a relative or friend of an adult, teen or child with IBS, or are a person with IBS with thoughts to share that would help family, friends, classmates, coworkers understand more about the challenges of living with moderate or severe IBS. Stories of self-advocacy are particularly of interest. Because the main website and this blog reach 91 countries worldwide, especially those where English is an official or major secondary language, we encourage international contributors who are able to write in English to participate and share experiences with IBS that are specific to culture, services and support systems for IBS in their home countries.

The IBS Impact administrators are also considering some future projects that may involve public awareness and are interested in hearing from people who are willing to be voices and faces for IBS and IBS Impact. None of your personal information or experiences will be used publicly without your explicit permission and involvement. However, because IBS Impact was founded, in part, specifically to encourage greater openness about IBS, we prefer to be able to use at least your first name.

If you are interested in contributing an article or becoming involved in public awareness, please use the contact links on the bottom of the  home page of the main website. We look forward to hearing from you.

Online Survey From the IBS Network in the United Kingdom

January 14, 2013

This blog’s many readers in the United Kingdom may be interested in the following short, anonymous online survey from the IBS Network.  The IBS Network, formerly known as The Gut Trust, is located in Sheffield and is the U.K.’s national organization for those with irritable bowel syndrome.

The seven question survey addresses respondents’ experiences with seeking advice or care from their doctors, experiences with the IBS Network, if any, and how the IBS Network might better meet the needs of people with IBS in the U.K. According to the IBS Network’s social media, answers to this survey will be helpful in their research. The survey can be accessed at the link below. Please address any questions or concerns about the survey directly to the IBS Network.

IBS Impact’s Top 10 Posts of 2012

January 7, 2013

This blog was begun in July 2011, a few months after the launch of the main IBS Impact website, and a bit over a year after the inception of IBS Impact itself. It is intended as a supplement to the many resources on our main site, one that can be updated relatively quickly with time-sensitive news, advocacy and clinical trial opportunities, as well as providing well-researched, scientifically reputable information on IBS and commentary on broader issues affecting the IBS community that may not be widely discussed on other sites. This blog is meant to be useful to a broad readership: people with IBS and related conditions, both those who may have lived with IBS for some time and those with recent onset or who are new to IBS sites online,  family members and friends, health care and human service professionals who may interact with us, and the general public.

Over time, it appears that it is increasingly filling this niche. According to WordPress statistics, this blog reached readers in 91 countries during 2012, the majority from nations where English is an official or major secondary language: the United States, the United Kingdom, Canada, Australia, Ireland, India and New Zealand, but on every continent, underscoring that IBS is a global problem, not the common stereotype of it as nuisance disorder caused by overindulgent North American lifestyles and diets. Some readers are regular followers, subscribed to the blog or followers of our Yahoo group, Facebook or Twitter. Many new readers find us daily through search engines, social media or links on other IBS or chronic illness sites.

Now that this blog has completed a full calendar year, it seems appropriate to participate in what is somewhat of a December-January tradition among many bloggers and review the individual posts with the most hits in 2012. As you will see, some of them were first published before 2012. However, they continue to attract attention  because they address topics that are of ongoing concern to people with IBS. Perhaps longtime readers can refresh their memories and newer readers will discover something interesting and useful.  In order, the posts are:

1. Functional Gastrointestinal Disorders/IBS Considered Presumptive Service-Connected Disabilities for U.S. Gulf War Veterans, 
August 12, 2011

2. 10 Things We Can Do for IBS Awareness This Month and Every Month, April 1, 2012

3. Food Poisoning and Post-Infectious IBS, August 5, 2011

4. Public Restroom Access and Irritable Bowel Syndrome (IBS),
February 21, 2012

5. IBS and Extraintestinal (Non-GI) Symptoms, September 6, 2011

6. Proposed DSM-5 Criteria May Unfairly Label Physical Conditions as Psychological Disorders, December 17, 2012

7. People With Disabilities (IBS or Other), Give Feedback to the U.S. Social Security Administration, January 17, 2012 
The specific advocacy opportunity in this post is no longer available, but general comments and resources on disability benefits in various countries remain valid.

8. For Children With IBS and Their Parents, April 11, 2012

9. Clinical Trial:Furiex Pharmaceuticals Investigational Medication for
IBS-D,  June 20, 2012

10. Irritable Bowel Syndrome (IBS) is Not a Diagnosis of Exclusion, October 9, 2011

IBS Impact wishes everyone a happy, healthy, prosperous and productive New Year and looks forward in 2013 to advances in awareness, advocacy, research, treatment and community support systems that benefit the worldwide IBS community.