Clinical Trial: DEFINE Study to Develop a Test for IBS at the University of North Carolina, August 2015

The University of North Carolina Center for Functional GI and Motility Disorders in Chapel Hill, one of the world’s major centers for diagnosis, treatment and research of irritable bowel syndrome is seeking adult volunteers for a study formally titled, “The development and validation of a blood test to identify IBS: DEFINE (Diagnostic Evaluation of IBS and Functional GI Networks.” The primary investigator is Yehuda Ringel, MD of UNC, and the IRB #is 13-2900.

Potential participants may be eligible for this study if they are at least 18 years old, have experienced any of the following gastrointestinal symptoms for at least 3-6 months without a definitive diagnosis or definitive testing: abdominal pain or discomfort, bloating, constipation and/or diarrhea.

Volunteers completing the study will receive up to $214 for their time and travel. Interested individuals should contact Charles Mclendon at 919-843-1003 or

The above information has been summarized from the Summer 2015 issue of Digest, the UNC Center quarterly newsletter Any questions or concerns should be directed to the UNC contact person above.

Previous posts on open clinical trials for IBS can be found by clicking the clinical trials category in the blog archives on the upper right sidebar of this blog. We also have a page for IBS studies on the main IBS Impact site. The research and links pages and the July 26, 2011 post provide additional general resources.

We welcome researchers affiliated with academic, medical or pharmaceutical entities, or reputable organizations representing IBS or related or commonly overlapping conditions, to contact us directly with additional studies they wish to be considered for posting. Contact links for the founder/listowner and the webmaster can be found on the home page of the main IBS Impact website.

IBS Impact makes these study announcements available for general information, and encourages its members and site visitors to make their own individual, informed choices about their potential participation in any study.  IBS Impact, as an entity, is not directly affiliated with any research sponsor and receives no funding from any source for studies or links we feature on this blog, the main site or social media.

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